Mismatch Probability (MMP) is a calculation of the probability of receiving a kidney offer with 0 and 1 broad HLA-A, -B or DR mismatches based on 1000 kidneys offered, taking into account ABO blood group rules and PRA screening. Patients receive between 0-100 MMPs
Usage
et_mmp(
data = candidates,
hlaA = hlaApt,
hlaB = hlaBpt,
hlaDR = hlaDRpt,
abo.freq = ABOpt,
check.validity = TRUE
)Arguments
- data
A data frame containing demographics and medical information for a group of waitlisted transplant candidates.
- hlaA
A data frame with HLA-A allele frequencies.
- hlaB
A data frame with HLA-B allele frequencies.
- hlaDR
A data frame with HLA-DR allele frequencies.
- abo.freq
A data frame with ABO blood group frequencies.
- check.validity
Logical to decide whether to validate input.
Value
A data table with columns for HLA allele frequencies and Mismatch Probability MMP (color priority),
Examples
et_mmp(data = candidates,
hlaA = hlaApt, hlaB = hlaBpt, hlaDR = hlaDRpt,
abo.freq = ABOpt, check.validity = TRUE)
#> bg abo DR2 DR2_freq DR1 DR1_freq B2 B2_freq B1 B1_freq A2
#> 1: A 0.4660 4 0.12983971 1 0.12189087 44 0.15036980 15 0.05647093 24
#> 2: O 0.4228 7 0.17697997 4 0.12983971 58 0.01871397 57 0.02859737 2
#> 3: O 0.4228 7 0.17697997 4 0.12983971 44 0.15036980 18 0.04769300 29
#> 4: O 0.4228 12 0.01538441 1 0.12189087 44 0.15036980 14 0.07571132 31
#> 5: O 0.4228 15 0.08401548 1 0.12189087 35 0.11773221 7 0.06018214 24
#> ---
#> 496: O 0.4228 14 0.02570210 13 0.15094886 51 0.10688811 49 0.03394046 68
#> 497: B 0.0769 8 0.04441608 3 0.10208460 51 0.10688811 8 0.06707815 29
#> 498: A 0.4660 13 0.15094886 1 0.12189087 27 0.03075567 14 0.07571132 33
#> 499: O 0.4228 7 0.17697997 16 0.02441239 44 0.15036980 39 0.01734530 33
#> 500: O 0.4228 4 0.12983971 11 0.10053168 37 0.01308136 35 0.11773221 32
#> A2_freq A1 A1_freq ID age dialysis cPRA urgent MMP0
#> 1: 0.10283473 2 0.27503751 1 53 59 0 0 3.871097e-04
#> 2: 0.27503751 1 0.10894112 2 41 35 16 0 3.106785e-05
#> 3: 0.05353618 25 0.01605559 3 72 53 0 0 1.788496e-05
#> 4: 0.02518885 2 0.27503751 4 48 50 0 0 8.681824e-05
#> 5: 0.10283473 3 0.10362435 5 62 39 0 0 5.720440e-05
#> ---
#> 496: 0.04998289 1 0.10894112 496 48 21 0 0 1.563121e-05
#> 497: 0.05353618 1 0.10894112 497 25 22 0 0 1.714726e-05
#> 498: 0.03511173 2 0.27503751 498 62 62 0 0 8.116832e-05
#> 499: 0.03511173 23 0.04510041 499 58 49 0 0 7.340246e-06
#> 500: 0.03917827 1 0.10894112 500 36 21 0 0 1.992446e-05
#> MMP2 MMP1 MMP
#> 1: 19.68507 0.0076202820 2.379158
#> 2: 81.97308 0.0025467271 40.014498
#> 3: 66.75502 0.0011939109 59.900904
#> 4: 30.96131 0.0026880059 30.916370
#> 5: 31.16391 0.0017827127 45.922285
#> ---
#> 496: 42.68281 0.0006671839 74.921003
#> 497: 42.51094 0.0007289461 94.423876
#> 498: 34.17044 0.0027735569 26.416335
#> 499: 63.83284 0.0004685488 81.772751
#> 500: 41.87166 0.0008342702 69.682657